|
Symbol Name ID |
Vegfa
vascular endothelial growth factor A MGI:103178 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cerebral hemorrhage |
Facial palsy |
Abnormal cerebral vascular morphology |
Stroke |
Dysphagia |
Vestibular schwannoma |
Bilateral vestibular schwannoma |
Unilateral vestibular schwannoma |
Neurofibroma |
Peripheral schwannoma |
Cerebral calcification |
Calcification of falx cerebri |
Abnormality of the nervous system |
Astrocytoma |
Glioma |
Ependymoma |
Neuroma |
Brain stem compression |
Hydrocephalus |
Abnormal cerebellum morphology |
Meningioma |
Intracranial meningioma |
Optic nerve sheath meningioma |
Spinal meningioma |
Myelopathy |
Spinal cord compression |
Spinal cord tumor |
Ataxia |
Hemiplegia/hemiparesis |
Hemiparesis |
Cranial nerve paralysis |
Aphasia |
Dysarthria |
Irritability |
Personality changes |
Polyphagia |
Hyperactivity |
Memory impairment |
Sleep abnormality |
Hyperreflexia |
Unsteady gait |
Postural instability |
Headache |
Peripheral neuropathy |
Mononeuropathy |
Polyneuropathy |
Sensory neuropathy |
Seizure |
Somatic sensory dysfunction |
Hyperesthesia |
Paresthesia |
| Disease(s) Associated with VEGFA | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Graves' disease | |||||||||||||||||||||||||||||||||||||||||||||||||||
| multiple myeloma | |||||||||||||||||||||||||||||||||||||||||||||||||||
| pre-eclampsia | |||||||||||||||||||||||||||||||||||||||||||||||||||
| pseudoxanthoma elasticum | |||||||||||||||||||||||||||||||||||||||||||||||||||
| vestibular schwannomatosis |
| Mouse Phenotypes | abnormal brain vasculature morphology |
increased neuron apoptosis |
increased embryonic neuroepithelium apoptosis |
abnormal neuronal migration |
abnormal neuron proliferation |
abnormal forebrain development |
hydrocephaly |
decreased brain size |
enlarged lateral ventricles |
abnormal choroid plexus morphology |
abnormal facial motor nucleus morphology |
abnormal cerebral cortex morphology |
astrocytosis |
motor neuron degeneration |
abnormal axon morphology |
decreased neuron number |
neuron degeneration |
abnormal somatic nervous system morphology |
abnormal cranial nerve morphology |
abnormal phrenic nerve morphology |
abnormal sciatic nerve morphology |
abnormal spinal cord ventral horn morphology |
neurodegeneration |
axon degeneration |
abnormal neuron physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||
| Vegfatm1Pec/Vegfatm1Pec | ||||||||||||||||||||||||||
| Vegfatm2Pec/Vegfatm2Pec | ||||||||||||||||||||||||||
| Vegfatm1Gne/Vegfa+ | ||||||||||||||||||||||||||
| Vegfatm2.1Nagy/Vegfa+ | ||||||||||||||||||||||||||
| Vegfatm2Gne/Vegfa+ Tg(Nes-cre)1Kln/0 (conditional) |
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| Vegfatm2Gne/Vegfatm2.1Nagy Tg(Nes-cre)1Kln/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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